Researchers have found that a carefully orchestrated act of X-chromosome 'yoyo' predicts the successful and efficient development of mammalian egg cells. The findings could pave the way for generating ...

Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

When the female germline develops, oocyte growth is accompanied by many changes in gene expression, however, the regulatory networks that control this process have not been determined. Now, a group of ...

Know how the ovarian microenvironment affects egg quality, fertility, and IVF success, and why this hidden factor plays a key ...

The new method offers researchers a powerful new platform to investigate the molecular mechanisms that control oogenesis, the process by which egg cells develop, and lays important groundwork for ...

A multi-institutional team of ovarian biologists and other reproductive specialists reports that putting an oocyte from an older mouse into the follicle of a young mouse can rejuvenate the oocyte, ...

In a new study published in the journal Nature, researchers in Japan report that activating just eight genes for producing gene-controlling proteins is enough to convert mouse stem cells directly into ...

An ovary is only a few centimeters wide, but its precious cargo is even smaller. Oocytes are a few dozen micrometers in diameter and are individually wrapped in layers of specialized cells that form a ...

Advances in reproductive science suggest that fertility is shaped not only by the number of eggs remaining in the ovaries, but also by the biological quality and cellular health of those eggs.