Scientists have found a way to map the intricate patterns of cells in mouse brain tissue with an off-the-shelf light microscope, using a trick that inflates a tiny sample to 16 times its original size ...

When designing microscopes, optical engineers have long faced a trade-off between speed, field of view and resolution. But ...

With a new microscope that's as light as a penny, researchers can now observe broad swaths of the brain in action as mice move about and interact with their environments. As a mouse explores its ...

Our brain is a complex organ. Billions of nerve cells are wired in an intricate network, constantly processing signals, enabling us to recall memories or to move our bodies. Making sense of this ...

A technique that supersizes cells to reveal minute details has gone big — really big. Using a polymer similar to those used in nappies to make them super-absorbent, scientists have expanded the volume ...

Researchers have incorporated a swept illumination source into an open-top light-sheet microscope to enable improved optical sectioning over a larger area of view. The advance makes the technique more ...

Summary: A research team reports the development of a high-resolution, adaptive light-sheet microscopy system capable of rapid, real-time 3D imaging of brain-wide seizure dynamics. By integrating an ...