Spatial ribonucleic acid (RNA) transcriptomics measures gene expression while preserving each molecule’s coordinates in intact tissue, tying transcripts to histology and local microenvironments.

Chang leads assay and applications development at Takara Bio, driving the commercialization of novel spatial genomics products. She has extensive experience in single-cell multiomics technologies and ...

Bulk RNA sequencing has advanced transcriptomic analysis across diverse biological systems, but averaging gene expression across cell populations can obscure important cellular differences.

Trends in liver metastases at diagnosis among young adults with colorectal cancer: A SEER-based analysis, 2010–2022. Genotype-directed targeted therapy combined with HAIC and tislelizumab for ...

Over the last few years, the single-cell landscape has transitioned from mapping individual cellular transcriptomes to ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

A group of a few dozen colorful translucent 3D blobs, many of which overlap, contain brightly colored dots against a black background. Three-dimensional transcriptomics data from an instrument ...

Spatial biology is a rapidly advancing discipline that examines biological molecules (such as DNA, RNA, and proteins) within their native locations in tissues. This approach offers critical insight ...

Larotrectinib in Patients With Tumors With NTRK Fusions: Results From the NCI-MATCH ECOG-ACRIN Trial (EAY131) Subprotocol EAY131-Z1E Advancements in profiling technologies have deepened our ...