Self‑replicating circular RNA persists in extreme environments: Insights from hot spring microbiomes

Although the genetic material of most living organisms is DNA, various self-replicating agents rely instead on RNA, including ...
ScienceAlert on MSN

This RNA almost self-replicates, which could explain life's origins

(Christoph Burgstedt/iStock/Getty Images Plus) The RNA world hypothesis posits that molecules made up of ribonucleic acids ...
Nature

Genotype-Phenotype Mapping and Evolutionary Dynamics in RNA

The relationship between RNA sequences and their resultant structures is central to understanding evolutionary processes and molecular robustness. Genotype–phenotype mapping studies reveal how subtle ...
Science Daily

Chemists recreate how RNA might have reproduced for first time

Chemists have demonstrated how RNA (ribonucleic acid) might have replicated itself on early Earth -- a key process in the origin of life. Chemists at UCL and the MRC Laboratory of Molecular Biology ...
Ars Technica

Tiny, 45 base long RNA can make copies of itself

There are plenty of unanswered questions about the origin of life on Earth. But the research community has largely reached consensus that one of the key steps was the emergence of an RNA molecule that ...
insider.si.edu

The RNA world : the nature of modern RNA suggests a prebiotic RNA world / edited by Raymond F. Gesteland, John F. Atkins

Prospects for understanding the origin of the RNA world / Gerald F. Joyce and Leslie E. Orgel -- Reading the palimpsest: contemporary biochemical data and the RNA world / Steven A. Benner ... [et al.] ...
GEN

RNA Expands Its Clinical Clout

DNA is the backbone of the genetic code so, logically, decoding and understanding the genetic sequence along with epigenetic modifications came first. Yet, RNA and the emerging field of ...
Nanowerk

A built-in 'hairpin' prevents rogue CRISPR RNAs

Bacteria independently evolved similar RNA hairpin structures to fix a wasteful flaw in different CRISPR immune systems, ...
eLife

New insights into the evolution of spider silk proteins illuminated by long-read transcriptomes

(spidroins) through long-read transcriptomics across a broad phylogenetic range, with theoretical implications for protein family evolution, biomaterials, and silk biology. By identifying putative ...
insider.si.edu

The RNA world : the nature of modern RNA suggests a prebiotic RNA / edited by Raymond F. Gesteland, Thomas R. Cech, John F. Atkins

Before RNA and after : geophysical and geochemical constraints on molecular evolution / Stephen J. Mojzsis, Ramanarayanan Krishnamurthy, and Gustaf Arrhenius -- Prospects for understanding the origin ...