Cells in the body have to move around in order to do their jobs. During development, for instance, cells are distributed to create and grow tissue. And in the event of an immune response, different ...
In the fast-evolving field of medical science, a new artificial intelligence model may be about to change the way mRNA-based drugs and vaccines are designed. Developed through a collaboration between ...
A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...
A research team headed by Heinrich Heine University Düsseldorf (HHU) has examined how the transport protein Rrm4 acts as a highly precise logistics expert in the fungus Ustilago maydis. Due to its ...
Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...
In this valuable study, the authors develop new approaches to investigate mRNA imprinting, a phenomenon in which RNA-protein complexes form in the nucleus to influence the fate of transcripts in the ...
A pizza shop with 30 delivery people ought to be able to deliver a lot of pizzas — if their cars don’t break down on the way. Likewise, genes that produce a lot of messenger RNA (mRNA) molecules can ...
The same groundbreaking technology that enabled rapid COVID-19 vaccine development is now poised to revolutionize medicine in ways that seemed impossible just a few years ago. Messenger RNA vaccines ...
Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that ...