Types A and B Niemann-Pick disease (NPD) are lipid storage diseases caused by the deficient activity of the lysosomal enzyme, acid sphingomyelinase (ASM). Type B NPD is associated with progressive ...
HIV-1-infected persons are at higher risk of lower respiratory tract infections than HIV-1-uninfected individuals. This suggests strongly that HIV-infected persons have specific impairment of ...
Scientists of Helmholtz Zentrum München, a partner in the German Center for Lung Research (DZL), have observed that the immunoproteasome inhibits the repair function of alveolar macrophages. This ...